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  1. Pahwa R, Stacy MA, Factor SA, et al, on behalf of the EASE-PD Adjunct Study Investigators. Ropinirole 24-hour prolonged release: randomized, controlled study in advanced Parkinson disease. Neurology. 2007;68:1108-1115.


  2. Data on file, GlaxoSmithKline.
  1. Tompson DJ, Vearer D. Steady-state pharmacokinetic properties of a 24-hour prolonged-release formulation of ropinirole: results of two randomized studies in patients with Parkinson's disease. Clin Ther. 2007;29:2654-2666.


  2. Prescribing Information for REQUIP XL.


Important Safety Information About REQUIP XL
  • Prescription REQUIP XL is not for everyone.
  • REQUIP XL may cause you to fall asleep or feel very sleepy during normal activities such as driving; or to faint or feel dizzy, nauseated, or sweaty when you stand up.
  • Tell your doctor if you experience these or the following problems, or if you drink alcohol or are taking other medicines that make you drowsy.
  • Side effects may include nausea, dizziness, drowsiness or sleepiness, headache, and sudden uncontrolled movements (dyskinesia).
  • Increase or decrease in blood pressure and heart rate may occur.
  • Hallucinations may occur at any time during treatment.
  • Also tell your doctor if you experience new or increased gambling, sexual, or other intense urges while taking REQUIP XL.
  • REQUIP XL may increase the side effects of L-dopa. Most patients were not bothered enough to stop taking REQUIP XL.