Dosing Guide
Provide new patients with a simple
titration schedule
- Initial dosage of 2 mg/day for 1 to 2 weeks.
- Increase dosage by 2 mg/day at 1 week or longer intervals as appropriate, depending on therapeutic response and tolerability, up to a maximally recommended dose of 24 mg/day.
- Caution should be exercised during dose titration because too rapid a rate of titration may lead to dose selection that may not provide additional benefit but may increase the risk of adverse reactions.
- Safety and effectiveness of REQUIP XL at doses greater than 24 mg/day have not been established.
Important Safety Information About REQUIP XL
REQUIP XL has been associated with sedating effects, including somnolence, and the possibility of falling asleep while engaged in activities of daily living, including operation of a motor vehicle. Syncope or symptomatic hypotension may occur more frequently during initial treatment or with an increase in dose. Increase in blood pressure and changes in heart rate may occur. Hallucinations may occur at any time during treatment. Impulse control symptoms, including pathological gambling and hypersexuality, have been reported in patients treated with dopaminergic agents, including ropinirole. REQUIP XL may potentiate the dopaminergic side effects of L-dopa and may cause and/or exacerbate pre-existing dyskinesia.